Ghali was born in 1989 in Paris, France and was raised in Athens, Greece to a Greek mother and Egyptian father. She is the oldest of two sisters. Ghali has been classically trained on the piano and flute since the age of 5. At the age of 15 she taught herself the guitar and the drums after forming a high school band in which she played lead guitar. During her time in the band, Ghali began songwriting. In 2008 she moved to the UK and studied music at the University of Surrey, earning a bachelor's degree in Creative Music Technology. In 2012 she moved to New York where she earned a Master's Degree from NYU (New York University) in Film Scoring, Music Composition and Production.